Nucleosome相关论文
k-mer usage in genome sequences is not random,the nonrandom evolution and its cause are worthy of special attention.Afte......
Background: Transcription factor (TF) binding at specific DNA sequences is the fundamental step in transcriptional regul......
The nucleosome is the basic structural repeating unit of chromatin which consists of double-stranded DNA(dsDNA)wrapp......
The basic unit of chromatin structure is the nucleosome, consisting of histone octamers wrapped in 147 base pairs of......
Background: CTCF is a versatile zinc finger DNA-binding protein that functions as a highly conserved epigenetic tran......
Pattern of nucleosome around single nucleotide polymorphism sites in genomic regions bound by transc
Background: Growing evidence indicates that nucleosome positioning has roles not only in regulating gene transcripti......
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Background: Meiotic recombination does not occur evenly across the genome, but instead occurs at relatively high fre......
Eukaryotic genomic DNA is packed into chromatin, whose fundamental structural unit is the nucleosome. As DNA-histone pro......
Chromatin and Nucleosome Organizations and DNA Replication of Nucleus Reassembled in vitro Using Pur
It has been demonstrated in the last ten years that the nuclear reassembly may occur in the cell-free systems from frog ......
Nucleosomal Context of Binding Sites Influences Transcription Factor Binding Affinity and Gene Regul
Transcription factor (TF) binding to its DNA target site plays an essential role in gene regulation.The location,orienta......
The polycomb repressive complexes 2 (PRC2) complex catalyzes tri-methylation of histone H3 lysine 27 (H3K27),a repressiv......
The establishment and faithful maintenance of epigenetic information in the context of chromatin are crucial for a great......
We have studied the dynamic process of interactions between a DNA chain and a histone octamer by numerical simulations. ......
Nucleosomes are fundamental units of chromatin that play critical roles in gene regulation by modulating DNA accessibili......
Nucleosomal Context of Binding Sites Influences Transcription Factor Binding Affinity and Gene Regul
本文通过对荣华二采区10...
本文通过对荣华二采区10...
计算了隔离子区的G和C占总碱基数的比例，统计分析了隔离子起始位点与终止位点上下游1000碱基对范围内核小体的平均占据，结果表明了隔......
染色质高度紧密的折叠阻止了转录因子和辅因子与DNA的结合,因而通过染色质重塑以解除这样的抑制环境,对于转录活动的正常进行是至......
应用有机汞亲和层析柱分离经微球菌核酸酶有限制消化的ＨＬ－６０细胞核，得到有机汞层析柱亲和及不亲和的２个核小体组分。琼脂糖凝胶电泳显示这......
目的将核小体Th表位与CTLA4Ig融合基因融合，研究CTLA4Ig作为真核表达载体的可行性。方法用touchdown PCR法扩增CTLA4Ig基因，同时引入......
在真核细胞中,核小体是组成染色质的基本结构单位,是由DNA紧密缠绕在组蛋白八聚体上所形成的一个复合体结构。而DNA与组蛋白的结合......
高迁移率族核小体结合蛋白（High-mobility group nucleosome-binding proteins,HMGN）几乎存在于所有哺乳动物和多数脊椎动物的细胞核......
染色质重塑是基因表达调控过程中一个非常重要的环节.染色质重塑主要包括2种类型:一种是依赖ATP的物理修饰,另一种是依赖共价结合......
在电镜下观察了大鼠肝细胞核和鸭红细胞核的核小体、30nm纤维和放射环等染色质结构。应用电子能量损失谱成像技术(ESI)对染色质中D......
在利用核小体定位实验数据训练支持向量机（SVM）对任意酵母DNA序列的核小体形成能力进行预测的过程中，发现染色质结构对基因组DNA分子......
采用从鸡血红细胞中分离纯化的组蛋白，从ＨｅＬａ细胞核中萃取的含有ＲＮＡ聚合酶Ⅱ和多种Ⅱ类基因转录因子的可溶性抽提物，以及从非洲爪蟾卵细胞核......
采用从鸡红细胞中分离纯化的组蛋白Ｈ１，核心组蛋白Ｈ２Ａ＋Ｈ２Ｂ和Ｈ３＋Ｈ４，以及从ＨｅＬａ细胞中萃取的含有ＲＮＡ聚合酶Ⅱ和多种Ⅱ类基因转录因子的可溶性ＨｅＬａ细胞核抽提物，通过......
基于酵母单碱基精度的核小体位置数据，提取核小体中心及连接序列分析两类序列的精细结构和模体偏好。结果显示，区分两类序列最主要的......
最原始的真核生物蓝氏贾第虫虽已有五种组蛋白,但以微球菌核酸酶水解却得不到规则的DNA片段.鉴于贾第虫的特殊进化地位,探讨其是否......
目的通过检测狼疮肾炎（LN）患儿肾脏中的组蛋白,探讨核小体在儿童LN肾脏中的沉积及可能的意义。方法用间接免疫荧光法检测27例LN患儿......
Nucleosomal Context of Binding Sites Influences Transcription Factor Binding Affinity and Gene Regul
Transcription factor (TF) binding to its DNA target site plays an essential role in gene regulation.The location,orienta......
本文对蚕豆根端分生组织细胞核中类胀泡结构的超微结构变化和细胞化学特点进行了研究。我们观察到,类胀泡结构是与集缩染色质紧密......
High mobility group protein 1: A collaborator in nucleosome dynamics and estrogen-responsive gene ex
High mobility group protein 1(HMGB1) is a multifunctional protein that interacts with DNA and chromatin to influence the......
Deformability of DNA is important for its superhelical folding in the nucleosome and has long been thought to be facilit......
